Understanding Enamel - Demineralisation and Remineralisation
Fluorides and their role in demineralization and remineralization
Soi.et.al- 2013
Relevance :
17 in 2024
Conclusion :
Mechanisams of action of Fl
1. Fluoride inhibits demineralization as the fluorapatite crystals, formed by reaction with enamel apatite crystals, are more resistant to acid attack compared to HAP crystals.
2.Fluoride enhances remineralization as it speeds up the growth of the new fluorapatite crystals by bringing calcium and phosphate ions together.
3.It inhibits the activity of acid producing carious bacteria, by interfering with the production of phosphoenol pyruvate (PEP) which is a key intermediate of the glycolytic pathway in bacteria.
4. Also, the F− retains on dental hard tissue, the oral mucosa and in the dental plaque to decrease demineralization and enhance remineralization.
Keywords:
Fluorides,
Demineralization,
Remineralization